Selecting PRP Kits

It is difficult to standardize PRP. This lack of standardization and consistency is prevalent throughout the literature and has made it to difficult to compare results between products and results. To determine the efficacy of PRP from system to system and patient to patient, the components of PRP and the delivery system to the target tissue site should be classified.

I propose the following classification for PRP (C.A.L.V.E.S.):

C = Platelet Concentration

A = Activated Endogenous (in tissue) or Exogenous (in a test tube)

L = Leukocyte Rich or Leukocyte Poor

V = Volume (low volume is <10cc) (high volume >10cc)

E = Extent of G-force (Fast spin or Slow Spin)

S = Single Spin or Multiple Spin

C	A	L	V	E	S
1.4	EXO	LP	LV 5-7 cc	5400 rpm	SS
3	EXO	LP	LV 5 cc	3000 rpm	SS
2	EXO	LP	LV 5 cc	2700 rpm	SS
2	EXO	LP	LV 5 cc	2500 rpm	SS
2	EXO	LP	LV 5 cc	3500 rpm	SS
2	EXO	LP	LV 5 cc	3000 rpm	SS

The most important factor is platelet concentration measurements of platelets.
The presence or absence of platelet activators, as well as the type of activator used, is also important.

For example, an exogenous platelet activator may be necessary to generate
a clot in certain procedures, whereas endogenous platelet activation without the use of an external clotting factor may be ideal for other indications.

Leukocyte concentration above baseline is also important to demonstrate whether a product is leukocyte is rich or poor.

The Volume in which is obtained is also important as different volumes are used for different applications
The final element to the classification is the Speed and type of centrifugal force on PRP